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Foxp3(+) CD25(–) CD4 T cells constitute a reservoir of committed regulatory cells that regain CD25 expression upon homeostatic expansion

Expression of the IL-2 receptor α chain (CD25) by peripheral CD4 T cells follows cellular activation. However, CD25 expression by CD4 cells is widely used as a marker to identify regulatory T cells (T(R)), although cells with regulatory properties are also found in the CD4(+)CD25(–) subset. By using...

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Detalhes bibliográficos
Main Authors: Zelenay, Santiago, Lopes-Carvalho, Thiago, Caramalho, Iris, Moraes-Fontes, Maria Francisca, Rebelo, Manuel, Demengeot, Jocelyne
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC554795/
https://ncbi.nlm.nih.gov/pubmed/15753306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408679102
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