VAMP3 and SNAP23 mediate the disturbed flow-induced endothelial microRNA secretion and smooth muscle hyperplasia

Vascular endothelial cells (ECs) at arterial branches and curvatures experience disturbed blood flow and induce a quiescent-to-activated phenotypic transition of the adjacent smooth muscle cells (SMCs) and a subsequent smooth muscle hyperplasia. However, the mechanism underlying the flow pattern-spe...

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Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Zhu, Juan-Juan, Liu, Yue-Feng, Zhang, Yun-Peng, Zhao, Chuan-Rong, Yao, Wei-Juan, Li, Yi-Shuan, Wang, Kuei-Chun, Huang, Tse-Shun, Pang, Wei, Wang, Xi-Fu, Wang, Xian, Chien, Shu, Zhou, Jing
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2017
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547597/
https://ncbi.nlm.nih.gov/pubmed/28716920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700561114
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