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Methodologies for Studying the Spliceosome's RNA Dynamics with Single-Molecule FRET
The spliceosome is an extraordinarily dynamic molecular machine in which significant changes in composition as well as protein and RNA conformation are required for carrying out pre-mRNA splicing. Single-molecule fluorescence resonance energy transfer (smFRET) can be used to elucidate these dynamics...
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| Publicado no: | Methods |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5546994/ https://ncbi.nlm.nih.gov/pubmed/28529063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2017.05.011 |
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