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Increasing the safety and efficacy of chimeric antigen receptor T cell therapy

Chimeric antigen receptor (CAR) T cell therapy is a promising cancer treatment that has recently been undergoing rapid development. However, there are still some major challenges, including precise tumor targeting to avoid off-target or “on-target/off-tumor” toxicity, adequate T cell infiltration an...

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Bibliografiske detaljer
Udgivet i:Protein Cell
Main Authors: Li, Hua, Zhao, Yangbing
Format: Artigo
Sprog:Inglês
Udgivet: Higher Education Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546931/
https://ncbi.nlm.nih.gov/pubmed/28434147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-017-0411-9
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