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The B chain of PDGF alone is sufficient for mitogenesis.

The platelet-derived growth factor (PDGF) is a mitogen derived from human platelets consisting of two related polypeptides termed A and B chains. The entire B chain of PDGF is highly (96%) homologous to a portion of p28sis, the transforming protein of simian sarcoma virus. It has been suggested that...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Kelly, J D, Raines, E W, Ross, R, Murray, M J
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1985
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC554676/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3004957/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1985.tb04096.x
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