Multimodal Analysis of Drug Transporter Expression in Gastrointestinal Tissue

OBJECTIVES: Drug transporters affect ART tissue disposition, but quantitative measures of drug transporter protein expression across pre-clinical species are not available. Our objective was to use proteomics to obtain absolute transporter concentrations and assess agreement with corresponding gene...

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Detalhes bibliográficos
Publicado no:AIDS
Main Authors: THOMPSON, Corbin G., FALLON, John K., MATHEWS, Michelle, CHARLINS, Paige, MULDER, Leila, KOVAROVA, Martina, ADAMSON, Lourdes, SRINIVAS, Nithya, SCHAUER, Amanda, SYKES, Craig, LUCIW, Paul, GARCIA, J. Victor, AKKINA, Ramesh, SMITH, Philip C., KASHUBA, Angela DM
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546623/
https://ncbi.nlm.nih.gov/pubmed/28590331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001554
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