Riluzole exerts distinct antitumor effects from a metabotropic glutamate receptor 1-specific inhibitor on breast cancer cells

Recent evidence suggests that glutamate signaling plays an important role in cancer. Riluzole is a glutamate release inhibitor and FDA-approved drug for the treatment of amyotrophic lateral sclerosis. It has been investigated as an inhibitor of cancer cell growth and tumorigenesis with the intention...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dolfi, Sonia C, Medina, Daniel J, Kareddula, Aparna, Paratala, Bhavna, Rose, Ashley, Dhami, Jatinder, Chen, Suzie, Ganesan, Shridar, Mackay, Gillian, Vazquez, Alexei, Hirshfield, Kim M
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546507/
https://ncbi.nlm.nih.gov/pubmed/28591718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17961
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