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Impact of chronic unpredicted mild stress-induced depression on repaglinide fate via glucocorticoid signaling pathway

Chronic unpredicted mild stress (CUMS)-induced depression could alter the pharmacokinetics of many drugs in rats, however, the underlying mechanism is not clear. In this work we studied the pharmacokinetics of repaglinide, and explored the role of glucocorticoid and adrenergic signaling pathway in r...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Wei, Hongyan, Zhou, Ting, Tan, Boyu, Zhang, Lei, Li, Mingming, Xiao, Zhijun, Xu, Feng
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546485/
https://ncbi.nlm.nih.gov/pubmed/28574832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17874
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