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Impact of chronic unpredicted mild stress-induced depression on repaglinide fate via glucocorticoid signaling pathway

Chronic unpredicted mild stress (CUMS)-induced depression could alter the pharmacokinetics of many drugs in rats, however, the underlying mechanism is not clear. In this work we studied the pharmacokinetics of repaglinide, and explored the role of glucocorticoid and adrenergic signaling pathway in r...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wei, Hongyan, Zhou, Ting, Tan, Boyu, Zhang, Lei, Li, Mingming, Xiao, Zhijun, Xu, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546485/
https://ncbi.nlm.nih.gov/pubmed/28574832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17874
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