EGF receptor lysosomal degradation is delayed in the cells stimulated with EGF-Quantum dot bioconjugate but earlier key events of endocytic degradative pathway are similar to that of native EGF

Quantum dots (QDs) complexed to ligands recognizing surface receptors undergoing internalization are an attractive tool for live cell imaging of ligand-receptor complexes behavior and for specific tracking of the cells of interest. However, conjugation of quasi-multivalent large QD-particle to monov...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Salova, Anna V., Belyaeva, Tatiana N., Leontieva, Ekaterina A., Kornilova, Elena S.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546484/
https://ncbi.nlm.nih.gov/pubmed/28574831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17873
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