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Simultaneous in vitro generation of CD8 and CD4 T cells specific to three universal tumor associated antigens of WT1, survivin and TERT and adoptive T cell transfer for the treatment of acute myeloid leukemia

Previously, we found that most patients with acute myeloid leukemia (AML) expressed at least one of the leukemic associated antigens (LAAs) WT1, survivin and TERT, and different combinations of the three LAAs predicted negative clinical outcomes. Multi-tumor antigen-specific T cells were generated t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Sohn, Hyun-Jung, Lee, Ji Yoon, Lee, Hyun-Joo, Sohn, Dae-Hee, Cho, Hyun-Il, Kim, Hee-Je, Kim, Tai-Gyu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546462/
https://ncbi.nlm.nih.gov/pubmed/28477011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17212
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