Simultaneous in vitro generation of CD8 and CD4 T cells specific to three universal tumor associated antigens of WT1, survivin and TERT and adoptive T cell transfer for the treatment of acute myeloid leukemia

Previously, we found that most patients with acute myeloid leukemia (AML) expressed at least one of the leukemic associated antigens (LAAs) WT1, survivin and TERT, and different combinations of the three LAAs predicted negative clinical outcomes. Multi-tumor antigen-specific T cells were generated t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sohn, Hyun-Jung, Lee, Ji Yoon, Lee, Hyun-Joo, Sohn, Dae-Hee, Cho, Hyun-Il, Kim, Hee-Je, Kim, Tai-Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546462/
https://ncbi.nlm.nih.gov/pubmed/28477011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17212
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