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Simultaneous in vitro generation of CD8 and CD4 T cells specific to three universal tumor associated antigens of WT1, survivin and TERT and adoptive T cell transfer for the treatment of acute myeloid leukemia

Previously, we found that most patients with acute myeloid leukemia (AML) expressed at least one of the leukemic associated antigens (LAAs) WT1, survivin and TERT, and different combinations of the three LAAs predicted negative clinical outcomes. Multi-tumor antigen-specific T cells were generated t...

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Foilsithe in:Oncotarget
Main Authors: Sohn, Hyun-Jung, Lee, Ji Yoon, Lee, Hyun-Joo, Sohn, Dae-Hee, Cho, Hyun-Il, Kim, Hee-Je, Kim, Tai-Gyu
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546462/
https://ncbi.nlm.nih.gov/pubmed/28477011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17212
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