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Whole-exome sequencing identified genetic risk factors for asparaginase-related complications in childhood ALL patients
Allergy, pancreatitis and thrombosis are common side-effects of childhood acute lymphoblastic leukemia (ALL) treatment that are associated with the use of asparaginase (ASNase), a key component in most ALL treatment protocols. Starting with predicted functional germline variants obtained through who...
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| Udgivet i: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Impact Journals LLC
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5546438/ https://ncbi.nlm.nih.gov/pubmed/28574850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17959 |
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