Mitochondrial ASncmtRNA-1 and ASncmtRNA-2 as potent targets to inhibit tumor growth and metastasis in the RenCa murine renal adenocarcinoma model

Knockdown of antisense noncoding mitochondrial RNAs (ASncmtRNAs) induces apoptosis in several human and mouse tumor cell lines, but not normal cells, suggesting this approach for a selective therapy against different types of cancer. Here we show that in vitro knockdown of murine ASncmtRNAs induces...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Borgna, Vincenzo, Villegas, Jaime, Burzio, Verónica A., Belmar, Sebastián, Araya, Mariela, Jeldes, Emanuel, Lobos-González, Lorena, Silva, Verónica, Villota, Claudio, Oliveira-Cruz, Luciana, Lopez, Constanza, Socias, Teresa, Castillo, Octavio, Burzio, Luis O.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Priority Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546434/
https://ncbi.nlm.nih.gov/pubmed/28620146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18460
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