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Transcriptome-wide noise controls lineage choice in mammalian progenitor cells
Phenotypic cell-to-cell variability within clonal populations may be a manifestation of “gene expression noise”(1–6), or it may reflect stable phenotypic variants(7). Such “non-genetic cell individuality”(7) can arise from the slow fluctuations of protein levels(8) in mammalian cells. These fluctuat...
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| Publicado no: | Nature |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5546414/ https://ncbi.nlm.nih.gov/pubmed/18497826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06965 |
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