Cylindromatosis Tumor Suppressor Protein (CYLD) Deubiquitinase is Necessary for Proper Ubiquitination and Degradation of the Epidermal Growth Factor Receptor

Cylindromatosis tumor suppressor protein (CYLD) is a deubiquitinase, best known as an essential negative regulator of the NFkB pathway. Previous studies have suggested an involvement of CYLD in epidermal growth factor (EGF)-dependent signal transduction as well, as it was found enriched within the t...

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Publicat a:Mol Cell Proteomics
Autors principals: Sanchez-Quiles, Virginia, Akimov, Vyacheslav, Osinalde, Nerea, Francavilla, Chiara, Puglia, Michele, Barrio-Hernandez, Inigo, Kratchmarova, Irina, Olsen, Jesper V., Blagoev, Blagoy
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546196/
https://ncbi.nlm.nih.gov/pubmed/28572092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.066423
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