Changes in Gab2 phosphorylation and interaction partners in response to interleukin (IL)-2 stimulation in T-lymphocytes

Interleukin-2 (IL-2) stimulation results in T-cell growth as a consequence of activation of highly sophisticated and fine-tuned signaling pathways. Despite lacking intrinsic enzymatic activity, scaffold proteins such as Gab2, play a pivotal role in IL-2-triggered signal transduction integrating, div...

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Vydáno v:Sci Rep
Hlavní autoři: Osinalde, Nerea, Sánchez-Quiles, Virginia, Blagoev, Blagoy, Kratchmarova, Irina
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4812247/
https://ncbi.nlm.nih.gov/pubmed/27025927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23530
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