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The molecular basis of the specific anti-influenza action of amantadine.

Amantadine (1-aminoadamantane hydrochloride) is effective in the prophylaxis and treatment of influenza A infections. In tissue culture this selective, strain-specific antiviral activity occurs at relatively low concentrations (5 microM or less), which inhibit either the initiation of infection or v...

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Détails bibliographiques
Auteurs principaux: Hay, A J, Wolstenholme, A J, Skehel, J J, Smith, M H
Format: Artigo
Langue:Inglês
Publié: 1985
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC554613/
https://ncbi.nlm.nih.gov/pubmed/4065098
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