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Mechanisms and regulation of DNA replication initiation in eukaryotes

Cellular DNA replication is initiated through the action of multiprotein complexes that recognize replication start sites in the chromosome (termed origins) and facilitate duplex DNA melting within these regions. In a given cell cycle, initiation occurs only once per origin and each round of replica...

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Detalhes bibliográficos
Publicado no:Crit Rev Biochem Mol Biol
Main Authors: Parker, Matthew W., Botchan, Michael R., Berger, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545932/
https://ncbi.nlm.nih.gov/pubmed/28094588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2016.1274717
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