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QbD based approach for optimization of Tenofovir disoproxil fumarate loaded liquid crystal precursor with improved permeability

BCS class III drugs suffer from a drawback of low permeability even though they have high aqueous solubility. The objective of current work was to screen the suitability of glyceryl monooleate (GMO)/Pluronic F127 cubic phase liquid crystals precursors for permeation enhancement and in turn the bioav...

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書目詳細資料
發表在:J Adv Res
Main Authors: Patil, Sharvil, Kadam, Chandrashekhar, Pokharkar, Varsha
格式: Artigo
語言:Inglês
出版: Elsevier 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545811/
https://ncbi.nlm.nih.gov/pubmed/28794904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jare.2017.07.005
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