Biomechanical strain exacerbates inflammation on a progeria-on-a-chip model

Organs-on-a-chip platforms seek to recapitulate the complex microenvironment of human organs using miniaturized microfluidic devices. Besides modeling healthy organs, these devices have been used to model diseases, yielding new insights into pathophysiology. Hutchinson-Gilford progeria syndrome (HGP...

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Udgivet i:Small
Main Authors: Ribas, João, Zhang, Yu Shrike, Pitrez, Patrícia R., Leijten, Jeroen, Miscuglio, Mario, Rouwkema, Jeroen, Dokmeci, Mehmet Remzi, Nissan, Xavier, Ferreira, Lino, Khademhosseini, Ali
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545787/
https://ncbi.nlm.nih.gov/pubmed/28211642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201603737
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