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Peptide and Peptide-Dependent Motions in MHC Proteins: Immunological Implications and Biophysical Underpinnings

Structural biology of peptides presented by class I and class II MHC proteins has transformed immunology, impacting our understanding of fundamental immune mechanisms and allowing researchers to rationalize immunogenicity and design novel vaccines. However, proteins are not static structures as ofte...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ayres, Cory M., Corcelli, Steven A., Baker, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545744/
https://ncbi.nlm.nih.gov/pubmed/28824655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00935
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