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Conditional Postnatal Deletion of the Neonatal Murine Hepatic Circadian Gene, Npas2, Alters the Gut Microbiome Following Restricted Feeding

BACKGROUND: We have recently shown in both non-human primates and in rodents that fetal and neonatal hepatic expression of the circadian transcription factor, Npas2, is modulated by a high fat maternal diet and plays a critical role in establishing life-long metabolic homeostasis. Similarly, we and...

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Foilsithe in:Am J Obstet Gynecol
Main Authors: O'neil, Derek S., Stewart, Christopher J., Chu, Derrick M., Goodspeed, Danielle M., Gonzalez-Rodriguez, Pablo J., Shope, Cynthia D., Aagaard, Kjersti M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5545073/
https://ncbi.nlm.nih.gov/pubmed/28373017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2017.03.024
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