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Pinus densiflora needle supercritical fluid extract suppresses the expression of pro-inflammatory mediators iNOS, IL-6 and IL-1β, and activation of inflammatory STAT1 and STAT3 signaling proteins in bacterial lipopolysaccharide-challenged murine macrophages

BACKGROUND: Regulation of a persistently-activated inflammatory response in macrophages is an important target for treatment of various chronic diseases. Pine needle extracts are well known to have potent immunomodulatory effects. The current study was designed to evaluate the effects of Pinus densi...

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Bibliografiske detaljer
Udgivet i:Daru
Main Authors: Venkatesan, Thamizhiniyan, Choi, Young-Woong, Lee, Jennifer, Kim, Young-Kyoon
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544993/
https://ncbi.nlm.nih.gov/pubmed/28778215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40199-017-0184-y
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