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Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7

c-Jun N-terminal kinase (JNK) is a member of the mitogen-activated protein kinase family and controls various physiological processes including apoptosis. A specific upstream activator of JNKs is the mitogen-activated protein kinase kinase 7 (MKK7). It has been reported that MKK7-JNK signaling plays...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yamasaki, Tokiwa, Deki-Arima, Norie, Kaneko, Asahito, Miyamura, Norio, Iwatsuki, Mamiko, Matsuoka, Masato, Fujimori-Tonou, Noriko, Okamoto-Uchida, Yoshimi, Hirayama, Jun, Marth, Jamey D., Yamanashi, Yuji, Kawasaki, Hiroshi, Yamanaka, Koji, Penninger, Josef M., Shibata, Shigenobu, Nishina, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544763/
https://ncbi.nlm.nih.gov/pubmed/28779160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07845-x
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