Vitamin D attenuates myofibroblast differentiation and extracellular matrix accumulation in nasal polyp-derived fibroblasts through smad2/3 signaling pathway

To investigate the potential role of vitamin D (1,25(OH)(2)D(3)) in preventing the development of nasal polyps, we examined the effect of vitamin D on myofibroblast differentiation and extracellular matrix (ECM) production in TGF-β1-induced nasal polyp-derived fibroblasts (NPDFs) and elucidated the...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Lee, Seoung-Ae, Yang, Hyun-Woo, Um, Ji-Young, Shin, Jae-Min, Park, Il-Ho, Lee, Heung-Man
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544725/
https://ncbi.nlm.nih.gov/pubmed/28779150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07561-6
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