Fucoxanthin Inhibits Myofibroblast Differentiation and Extracellular Matrix Production in Nasal Polyp-Derived Fibroblasts via Modulation of Smad-Dependent and Smad-Independent Signaling Pathways

Nasal polyps (NPs) are a multifactorial disorder associated with a chronic inflammatory state of the nasal mucosa. Fucoxanthin (Fx) is a characteristic orange carotenoid obtained from brown algae and has diverse immunological properties. The present study investigated whether Fx inhibits fibrosis-re...

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Udgivet i:Mar Drugs
Main Authors: Jung, Hyun, Lee, Dae-Sung, Park, Seong Kook, Choi, Jung Sik, Jung, Won-Kyo, Park, Won Sun, Choi, Il-Whan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6165344/
https://ncbi.nlm.nih.gov/pubmed/30201895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16090323
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