CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation

The NLRP3 inflammasome can sense different pathogens or danger signals, and has been reported to be involved in the development of many human diseases. Potassium efflux and mitochondrial damage are both reported to mediate NLRP3 inflammasome activation, but the underlying, orchestrating signaling ev...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Tang, Tiantian, Lang, Xueting, Xu, Congfei, Wang, Xiaqiong, Gong, Tao, Yang, Yanqing, Cui, Jun, Bai, Li, Wang, Jun, Jiang, Wei, Zhou, Rongbin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544706/
https://ncbi.nlm.nih.gov/pubmed/28779175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00227-x
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