D4F alleviates macrophage-derived foam cell apoptosis by inhibiting the NF-κB-dependent Fas/FasL pathway

This study was designed to explore the protective effect of D4F, an apolipoprotein A-I mimetic peptide, on nuclear factor-κB (NF-κB)-dependent Fas/Fas ligand (FasL) pathway-mediated apoptosis in macrophages induced by oxidized low-density lipoprotein (ox-LDL). Our results showed that ox-LDL induced...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Tian, Hua, Yao, Shu-tong, Yang, Na-na, Ren, Jie, Jiao, Peng, Zhang, Xiangjian, Li, Dong-xuan, Zhang, Gong-an, Xia, Zhen-fang, Qin, Shu-cun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544683/
https://ncbi.nlm.nih.gov/pubmed/28779128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07656-0
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