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RNA SEQ Analysis Indicates that the AE3 Cl(−)/HCO(3)(−) Exchanger Contributes to Active Transport-Mediated CO(2) Disposal in Heart

Loss of the AE3 Cl(−)/HCO(3) (−) exchanger (Slc4a3) in mice causes an impaired cardiac force-frequency response and heart failure under some conditions but the mechanisms are not known. To better understand the functions of AE3, we performed RNA Seq analysis of AE3-null and wild-type mouse hearts an...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Vairamani, Kanimozhi, Wang, Hong-Sheng, Medvedovic, Mario, Lorenz, John N., Shull, Gary E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544674/
https://ncbi.nlm.nih.gov/pubmed/28779178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07585-y
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