Niclosamide and bicalutamide combination treatment overcomes enzalutamide and bicalutamide resistant prostate cancer

Activation of the androgen receptor (AR) and its splice variants is linked to advanced prostate cancer and drives resistance to antiandrogens. The roles of AR and AR variants in the development of resistance to androgen deprivation therapy (ADT) and bicalutamide treatment, however, are still incompl...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Liu, Chengfei, Armstrong, Cameron M., Lou, Wei, Lombard, Alan P., Cucchiara, Vito, Gu, Xinwei, Yang, Joy C., Nadiminty, Nagalakshmi, Pan, Chong-xian, Evans, Christopher P., Gao, Allen C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544572/
https://ncbi.nlm.nih.gov/pubmed/28500234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0912
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