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Niclosamide suppresses cell migration and invasion in enzalutamide resistant prostate cancer cells via Stat3-AR axis inhibition

PURPOSE: It is known that over expression of IL6 in prostate cancer cells confer enzalutamide resistance and that this may occur through constitutive Stat3 activation. Additionally, recent pre-clinical studies suggested enzalutamide might have the potential adverse effect of inducing metastasis of p...

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Detalhes bibliográficos
Publicado no:Prostate
Main Authors: Liu, Chengfei, Lou, Wei, Armstrong, Cameron, Zhu, Yezi, Evans, Christopher P, Gao, Allen C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536195/
https://ncbi.nlm.nih.gov/pubmed/25970160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23015
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