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Distinct regulatory mechanisms control proinflammatory cytokines IL-18 and IL-1β
IL-18 and IL-1β, which are cytokines of the IL-1 family, are synthesized as precursor proteins and activated by the inflammasome via proteolytic processing. IL-1β is induced only in response to inflammatory stimuli, but IL-18 is constitutively expressed. However, how IL-18 and IL-1β expression is re...
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| Publicado no: | J Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5544497/ https://ncbi.nlm.nih.gov/pubmed/28468974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700352 |
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