Using Postmortem hippocampi tissue can interfere with differential gene expression analysis of the epileptogenic process

Neuropathological studies often use autopsy brain tissue as controls to evaluate changes in protein or RNA levels in several diseases. In mesial temporal lobe epilepsy (MTLE), several genes are up or down regulated throughout the epileptogenic and chronic stages of the disease. Given that postmortem...

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Pubblicato in:PLoS One
Autori principali: Born, João Paulo Lopes, Matos, Heloisa de Carvalho, de Araujo, Mykaella Andrade, Castro, Olagide Wagner, Duzzioni, Marcelo, Peixoto-Santos, José Eduardo, Leite, João Pereira, Garcia-Cairasco, Norberto, Paçó-Larson, Maria Luisa, Gitaí, Daniel Leite Góes
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544225/
https://ncbi.nlm.nih.gov/pubmed/28783762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182765
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