Using Postmortem hippocampi tissue can interfere with differential gene expression analysis of the epileptogenic process

Neuropathological studies often use autopsy brain tissue as controls to evaluate changes in protein or RNA levels in several diseases. In mesial temporal lobe epilepsy (MTLE), several genes are up or down regulated throughout the epileptogenic and chronic stages of the disease. Given that postmortem...

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Udgivet i:PLoS One
Main Authors: Born, João Paulo Lopes, Matos, Heloisa de Carvalho, de Araujo, Mykaella Andrade, Castro, Olagide Wagner, Duzzioni, Marcelo, Peixoto-Santos, José Eduardo, Leite, João Pereira, Garcia-Cairasco, Norberto, Paçó-Larson, Maria Luisa, Gitaí, Daniel Leite Góes
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544225/
https://ncbi.nlm.nih.gov/pubmed/28783762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182765
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