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miR-34a and miR-9 are overexpressed and SIRT genes are downregulated in peripheral blood mononuclear cells of aging humans

Increased expression of sirtuins lowers the risk of age-related diseases, while their role in the regulation of longevity is not firmly established. Since aging is associated with immunosenescence, we tested whether sirtuin expression was modified in peripheral blood mononuclear cells (PBMC) in an a...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Owczarz, Magdalena, Budzinska, Monika, Domaszewska-Szostek, Anna, Borkowska, Joanna, Polosak, Jacek, Gewartowska, Magdalena, Slusarczyk, Przemyslaw, Puzianowska-Kuznicka, Monika
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544174/
https://ncbi.nlm.nih.gov/pubmed/28699360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370217720884
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