miR-96, miR-145 and miR-9 expression increases, and IGF-1R and FOXO1 expression decreases in peripheral blood mononuclear cells of aging humans

BACKGROUND: In mammals, the IGF-1 pathway affects the phenotype of aging. Since the function of the immune system is modulated by IGF-1, it is plausible that immunosenescence might in part result from altered control by this pathway. We therefore examined whether the expression of IGF-1R, FOXO1, and...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Geriatr
Egile Nagusiak: Budzinska, Monika, Owczarz, Magdalena, Pawlik-Pachucka, Eliza, Roszkowska-Gancarz, Malgorzata, Slusarczyk, Przemyslaw, Puzianowska-Kuznicka, Monika
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131432/
https://ncbi.nlm.nih.gov/pubmed/27903254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12877-016-0379-y
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