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The roles of RNA processing in translating genotype to phenotype

A goal of human genetics studies is to determine the mechanisms by which genetic variation produces phenotypic differences that affect human health. Efforts in this respect have previously focused on genetic variants that affect mRNA levels by altering epigenetic and transcriptional regulation. Rece...

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Detalhes bibliográficos
Publicado no:Nat Rev Mol Cell Biol
Main Authors: Manning, Kassie S., Cooper, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544131/
https://ncbi.nlm.nih.gov/pubmed/27847391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm.2016.139
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