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The role of HFE genotype in macrophage phenotype

BACKGROUND: Iron regulation is essential for cellular energy production. Loss of cellular iron homeostasis has critical implications for both normal function and disease progression. The H63D variant of the HFE gene is the most common gene variant in Caucasians. The resulting mutant protein alters c...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Nixon, Anne M., Neely, Elizabeth, Simpson, Ian A., Connor, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796391/
https://ncbi.nlm.nih.gov/pubmed/29391061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1057-0
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