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The role of HFE genotype in macrophage phenotype

BACKGROUND: Iron regulation is essential for cellular energy production. Loss of cellular iron homeostasis has critical implications for both normal function and disease progression. The H63D variant of the HFE gene is the most common gene variant in Caucasians. The resulting mutant protein alters c...

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Pubblicato in:J Neuroinflammation
Autori principali: Nixon, Anne M., Neely, Elizabeth, Simpson, Ian A., Connor, James R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796391/
https://ncbi.nlm.nih.gov/pubmed/29391061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1057-0
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