Mixed-lineage kinase 3 pharmacological inhibition attenuates murine nonalcoholic steatohepatitis

With the increase in obesity worldwide, its associated comorbidities, including nonalcoholic steatohepatitis (NASH), have become a public health problem that still lacks effective therapy. We have previously reported that mixed-lineage kinase 3–deficient (MLK3-deficient) mice are protected against d...

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Pubblicato in:JCI Insight
Autori principali: Tomita, Kyoko, Kohli, Rohit, MacLaurin, Brittany L., Hirsova, Petra, Guo, Qianqian, Sanchez, Luz H. Gutierrez, Gelbard, Harris A., Blaxall, Burns C., Ibrahim, Samar H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543922/
https://ncbi.nlm.nih.gov/pubmed/28768902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94488
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