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CXCL10-Mediates Macrophage, but not Other Innate Immune Cells-Associated Inflammation in Murine Nonalcoholic Steatohepatitis

Nonalcoholic steatohepatitis (NASH) is an inflammatory lipotoxic disorder, but how inflammatory cells are recruited and activated within the liver is still unclear. We previously reported that lipotoxic hepatocytes release CXCL10-enriched extracellular vesicles, which are potently chemotactic for ce...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tomita, Kyoko, Freeman, Brittany L., Bronk, Steven F., LeBrasseur, Nathan K., White, Thomas A., Hirsova, Petra, Ibrahim, Samar H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923862/
https://ncbi.nlm.nih.gov/pubmed/27349927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28786
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