High pathogen burden in childhood promotes the development of unconventional innate-like CD8(+) T cells

Cellular and humoral constituents of the immune system differ significantly between children and adults, yet very little is known about the impact of early-life pathogen exposure on this immunologic transition. We examined CD4(+) and CD8(+) T cell subsets defined by CCR7 and CD45RA expression in two...

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Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Falanga, Yves T., Frascoli, Michela, Kaymaz, Yasin, Forconi, Catherine, Ong’echa, John Michael, Bailey, Jeffrey A., Berg, Leslie J., Moormann, Ann M.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543908/
https://ncbi.nlm.nih.gov/pubmed/28768916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93814
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