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High pathogen burden in childhood promotes the development of unconventional innate-like CD8(+) T cells
Cellular and humoral constituents of the immune system differ significantly between children and adults, yet very little is known about the impact of early-life pathogen exposure on this immunologic transition. We examined CD4(+) and CD8(+) T cell subsets defined by CCR7 and CD45RA expression in two...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5543908/ https://ncbi.nlm.nih.gov/pubmed/28768916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93814 |
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