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Mutations within the 23S rRNA coding sequence of E. coli which block ribosome assembly.

We have used site specific mutagenesis in vitro to construct a set of deletion mutations within the 5' region of a cloned 23S rRNA gene. In contrast to previously studied mutations in this gene, some of these deletions prevent the incorporation of 23S rRNA into ribosomal particles. This result...

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Bibliografische gegevens
Hoofdauteurs: Skinner, R H, Stark, M J, Dahlberg, A E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1985
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC554389/
https://ncbi.nlm.nih.gov/pubmed/3896776
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