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Human cutaneous melanoma; a review of NRAS and BRAF mutation frequencies in relation to histogenetic subclass and body site
A majority of cutaneous melanomas show activating mutations in the NRAS or BRAF proto‐oncogenes, components of the Ras‐Raf‐Mek‐Erk signal transduction pathway. Consistent data demonstrate the early appearance, in a mutually exclusive manner, of these mutations. The purpose of this paper is to summar...
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| Опубликовано в: : | Mol Oncol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5543839/ https://ncbi.nlm.nih.gov/pubmed/19383313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2007.12.003 |
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