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Reparameterization of Protein Force Field Nonbonded Interactions Guided by Osmotic Coefficient Measurements from Molecular Dynamics Simulations

There is a small, but growing, body of literature describing the use of osmotic coefficient measurements to validate and reparameterize simulation force fields. Here we have investigated the ability of five very commonly used force field and water model combinations to reproduce the osmotic coeffici...

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Bibliographische Detailangaben
Veröffentlicht in:J Chem Theory Comput
Hauptverfasser: Miller, Mark S., Lay, Wesley K., Li, Shuxiang, Hacker, William C., An, Jiadi, Ren, Jianlan, Elcock, Adrian H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543770/
https://ncbi.nlm.nih.gov/pubmed/28296391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.6b01059
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