Baicalin attenuates chronic hypoxia-induced pulmonary hypertension via adenosine A(2A) receptor-induced SDF-1/CXCR4/PI3K/AKT signaling

BACKGROUND: Baicalin, an important flavonoid in Scutellaria baicalensis Georgi extracts, exerts a variety of pharmacological effects. In this study, we explored the effects of baicalin on chronic hypoxia-induced pulmonary arterial hypertension (PAH) and investigated the mechanism underlying these ef...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Huang, Xiaoying, Wu, Peiliang, Huang, Feifei, Xu, Min, Chen, Mayun, Huang, Kate, Li, Guo-ping, Xu, Manhuan, Yao, Dan, Wang, Liangxing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543745/
https://ncbi.nlm.nih.gov/pubmed/28774332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-017-0359-3
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