Baicalin attenuates bleomycin-induced pulmonary fibrosis via adenosine A2a receptor related TGF-β1-induced ERK1/2 signaling pathway

BACKGROUND: Baicalin has been reported to have anti-fibrosis effect; however, its mechanism still remains to be elucidated. Adenosine A2a receptor (A2aR) is a novel inflammation regulator, and transforming growth factor-β1 (TGF-β1)-induced extracellular signal regulated kinase1/2 (ERK1/2) signaling...

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Publicat a:BMC Pulm Med
Autors principals: Huang, Xiaoying, He, Yicheng, Chen, Yanfan, Wu, Peiliang, Gui, Di, Cai, Hui, Chen, Ali, Chen, Mayun, Dai, Caijun, Yao, Dan, Wang, Liangxing
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034677/
https://ncbi.nlm.nih.gov/pubmed/27658704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-016-0294-1
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