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The chicken or the egg: mitochondrial dysfunction and oxidative damage as a cause or consequence of on toxicity in Huntington’s disease

Mitochondrial dysfunction and ensuing oxidative damage is typically thought to be a primary cause of Huntington’s disease, Alzheimer’s disease and Parkinson disease. There is little doubt that mitochondria (MT) become defective as neurons die, yet whether MT defects are the primary cause or a detrim...

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Publicat a:Mech Ageing Dev
Autors principals: Polyzos, Aris A., McMurray, Cynthia T.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5543717/
https://ncbi.nlm.nih.gov/pubmed/27634555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2016.09.003
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