Proteomics Unravels Emodin Causes Liver Oxidative Damage Elicited by Mitochondrial Dysfunction

Emodin is one of the main active compounds in many Chinese traditional herbs. Due to its potential toxic effect on the liver, the possible injury mechanism needs to be explored. In the present study, we investigated liver injury mechanisms of emodin on rats by the technology of proteomics. Firstly,...

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Detaylı Bibliyografya
Asıl Yazarlar: Yinhuan Zhang, Xiaowei Yang, Zhixin Jia, Jie Liu, Xiaoning Yan, Yihang Dai, Hongbin Xiao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2020-04-01
Seri Bilgileri:Frontiers in Pharmacology
Konular:
Emodin
liver injury
proteomics
mitochondrial dysfunction
redox homeostasis
Online Erişim:https://www.frontiersin.org/article/10.3389/fphar.2020.00416/full
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