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Differential methylation of the c-H-ras gene in normal mouse cells and during skin tumour progression.

We have previously shown that the mouse c-H-ras gene acquires transforming activity in chemically induced skin tumours. We have now investigated the pattern of DNA methylation at HpaII and XhoI sites around the c-H-ras locus in various tissues and stages of epidermal tumour progression. The results...

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Dettagli Bibliografici
Autori principali: Ramsden, M, Cole, G, Smith, J, Balmain, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1985
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC554366/
https://ncbi.nlm.nih.gov/pubmed/4029120
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